Detalhe da pesquisa
1.
High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against nontuberculous mycobacteria in vitro and in vivo.
J Biol Chem
; 300(2): 105618, 2024 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-38176652
2.
An essential protease, FtsH, influences daptomycin resistance acquisition in Enterococcus faecalis.
Mol Microbiol
; 2024 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38527904
3.
HflX is a GTPase that controls hypoxia-induced replication arrest in slow-growing mycobacteria.
Proc Natl Acad Sci U S A
; 118(12)2021 03 23.
Artigo
Inglês
| MEDLINE | ID: mdl-33723035
4.
Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosis Cytochrome bcc:aa3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome cI.
Antimicrob Agents Chemother
; 67(6): e0153122, 2023 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37158740
5.
Designer broad-spectrum polyimidazolium antibiotics.
Proc Natl Acad Sci U S A
; 117(49): 31376-31385, 2020 12 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33229526
6.
Sensitivity of Mycobacterium leprae to Telacebec.
Emerg Infect Dis
; 28(3): 749-751, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35202539
7.
New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis.
PLoS Pathog
; 16(1): e1008270, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31971990
8.
Nontoxic Antimicrobial Cationic Peptide Nanoconstructs with Bacteria-Displaceable Polymeric Counteranions.
Nano Lett
; 21(2): 899-906, 2021 01 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33448223
9.
The QcrB Inhibitors TB47 and Telacebec Do Not Potentiate the Activity of Clofazimine in Mycobacterium abscessus.
Antimicrob Agents Chemother
; 65(12): e0096421, 2021 11 17.
Artigo
Inglês
| MEDLINE | ID: mdl-34543090
10.
Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria.
J Biol Chem
; 294(6): 1936-1943, 2019 02 08.
Artigo
Inglês
| MEDLINE | ID: mdl-30530783
11.
Toward a Single-Dose Cure for Buruli Ulcer.
Antimicrob Agents Chemother
; 64(9)2020 08 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32631818
12.
Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection.
Proc Natl Acad Sci U S A
; 114(28): 7426-7431, 2017 07 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28652330
13.
A Glycosylated Cationic Block Poly(ß-peptide) Reverses Intrinsic Antibiotic Resistance in All ESKAPE Gram-Negative Bacteria.
Angew Chem Int Ed Engl
; 59(17): 6819-6826, 2020 04 20.
Artigo
Inglês
| MEDLINE | ID: mdl-32011781
14.
Discovery of a Novel Mycobacterial F-ATP Synthase Inhibitor and its Potency in Combination with Diarylquinolines.
Angew Chem Int Ed Engl
; 59(32): 13295-13304, 2020 08 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32337801
15.
Target Engagement and Binding Mode of an Antituberculosis Drug to Its Bacterial Target Deciphered in Whole Living Cells by NMR.
Biochemistry
; 58(6): 526-533, 2019 02 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30521325
16.
Bedaquiline Inhibits the ATP Synthase in Mycobacterium abscessus and Is Effective in Infected Zebrafish.
Antimicrob Agents Chemother
; 61(11)2017 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28807917
17.
The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPD.
Respirology
; 22(4): 634-650, 2017 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28342288
18.
Microbiomes in respiratory health and disease: An Asia-Pacific perspective.
Respirology
; 22(2): 240-250, 2017 02.
Artigo
Inglês
| MEDLINE | ID: mdl-28102970
19.
Isolation and Characterization of a Hybrid Respiratory Supercomplex Consisting of Mycobacterium tuberculosis Cytochrome bcc and Mycobacterium smegmatis Cytochrome aa3.
J Biol Chem
; 290(23): 14350-60, 2015 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25861988
20.
Contribution of high-content imaging technologies to the development of anti-infective drugs.
Cytometry A
; 89(8): 755-60, 2016 08.
Artigo
Inglês
| MEDLINE | ID: mdl-27272127